Jarrett Adams, PhD
Technical Advisor, Protein Engineering
Jarrett is a protein engineer who specializes in synthetic antibody technologies. He trained as a structural biologist and spent 3 years at Stanford University studying immune recognition, and 10 years at University of Toronto as the Associate Director of the Toronto Recombinant Antibody Centre (TRAC). He developed a state-of-the-art antibody discovery platform utilized by academics and pharmaceutical companies, conducted research in cancer biology, immune-oncology, regenerative medicine and infectious disease. He has participated in several drug development programs with Celgene, Pionyr Therapeutics, Northern Biologics and Reflexion Pharmaceuticals. His research work has been at the forefront of understanding underlying synthetic molecular technologies for the development of biologics platforms. Platforms developed by Jarrett have been used to characterize T cell-pMHC recognition networks as well as to build a catalog of 15,000 mAb targeting the human surfaceome. Likewise, Jarrett engineered these synthetic technologies to manipulate signaling in disease through synthetic modality configurations including tailored inhibitors in oncology, bispecific modalities in immune-oncology and tetravalent synthetic agonists in regenerative medicine. Jarrett has authored and co-authored over 38 articles in peer-reviewed journals including Immunity and PNAS. Jarrett holds a PhD in Biochemistry from Queen’s University which was awarded the Governor General’s Academic Medal.